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lating the Th1/Th2 balance via the JAK/STAT signaling pathway. Sida cordifolia is traditionally found in the Indian system of medicine, well known for its medicinal and nutritional properties among local natives. The present study aims to investigate the osteo-protective effect of root and leaf ethanolic extract of S. cordifolia (RE and LE) and its underlying mechanism. Antioxidant activity of RE and LE was assessed. Total phenolic and flavonoid content were determined. HPLC profiling of RE and LE was performed to examine the polyphenol content. The effect
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