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5 exposure and preterm birth, as well as the combined effects of PM2.5 exposure and temperature on preterm birth. Result In a model that includes three trimesters of PM2.5 and temperature data as exposures, which assumes an interaction between PM2.5 and temperature in each trimester, the risk of preterm birth was positively associated with TR1 PM2.5 exposure among pregnant women exposed to relatively low mean temperatures ( less then 3.4 °C) during TR1 (OR 1.134, 95% CI 1.061-1.213, p less then 0.001). Conclusions When we assumed the in
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