https://www.selleckchem.com/pr....oducts/etomoxir-na-s
Aim Understanding a drug dissolution process from solid dispersions (SD) to develop formulations with predictable in vivo performance. Materials methods Dissolution data of fenbendazole released from the SDs and the control physical mixtures were analyzed using the Lumped mathematical model to estimate the parameters of pharmaceutical relevance. Results The fit data obtained by Lumped model showed that all SDs have a unique dissolution profile with an error of ±4.1% and an initial release rate 500-times higher than the pu