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We aimed to investigate the association between cerebral arteriosclerosis stenosis (CAS) and the short-term prognosis of non-valvular atrial fibrillation (NVAF) related cardioembolic stroke treated by reperfusion therapy. The data of 195 consecutive NVAF related cardioembolic stroke patients were retrospectively collected. We defined poor functional outcome as a modified Rankin scale (mRS) score of 2 at 90 days. Patients with CAS were more likely to be older (75.5±6.8 vs. 72.5±9.2 years, p=0.001), more current smokers (35.6% vs. 24.1%,