https://www.selleckchem.com/pr....oducts/PD-0325901.ht
Our results indicate that an acidic environment is essential for CARDS toxin retrograde transport to endoplasmic reticulum. Moreover, retrograde transport facilitates toxin clipping and is required to induce vacuole formation. Additionally, toxin-mediated cell vacuolation is strictly dependent on the function of vacuolar type-ATPase.The shift in climate regimes around 1970s caused an overall enhancement of precipitation extremes across the globe with a specific spatial distribution pattern. We used gridded observational-reanalysis pr
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