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To compare long-term outcomes between photoselective vaporization (PVP) and Open simple prostatectomy (OSP) for prostates 80cc. Men operated either by PVP or OSP for BPH 80cc were included in two expert centres. Functional and uroflowmetric outcomes were assessed pre- and postoperatively. Data were collected prospectively in the PVP group and retrospectively in the OSP group and compared at long-term follow-up. Complications and re-intervention rates were used as main outcomes. 332 men underwent surgery 132 PVP were performed in