https://www.selleckchem.com/pr....oducts/sar439859.htm
Acute pancreatitis is a common inflammatory disorder of the exocrine pancreas with no specific therapy. Intracellular nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in nicotinamide adenine dinucleotide (NAD) salvage pathway, is involved in many inflammatory disorders. In this study, we investigated the role of NAMPT in experimental acute pancreatitis. Acute pancreatitis was induced in mice using three disparate models (1) caerulein hyperstimulation, (2) ethanol plus palmitoleic acid, and (3) retrograde biliop
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