https://www.selleckchem.com/pr....oducts/kb-0742-dihyd
In addition, CYP1A2 KO rats exhibited a significant increase in serum cholesterol and free testosterone, accompanied by mild liver damage and lipid deposition, suggesting CYP1A2 deficiency affects lipid metabolism and liver function in rats to some extent. In summary, we successfully constructed the CYP1A2 KO rat model, which provides a useful tool for studying the metabolic function and physiological function of CYP1A2. Significance Statement Human CYP1A2 not only metabolizes clinical drugs and pollutants, but also medi
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