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More over, AOA plus regorafenib, an FDA-proved medication for hepatocellular carcinoma and colorectal cancer tumors, achieved a far better anti-tumor impact on tumors carrying the p5372P variation. Consequently, our findings identified an increase of purpose of the p5372P variant on mitochondrial function and offered a promising accuracy strategy to treat tumors vulnerable to p5372P-PSAT1 perturbation.The biological characteristics associated with the temporomandibular