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8 % during the study period. There was a statistically significant interaction between traumatic injury death and AOD on both an additive scale and multiplicative scale. (Odds Ratio for interaction term = 1.76, 95 % CI = 1.53, 2.03). AOD use does not provide a protective benefit in the setting of trauma, but rather is an important contributor to traumatic injury mortality. AOD use does not provide a protective benefit in the setting of trauma, but rather is an important contributor to traumatic injury mortality. Both marijuana and other