https://www.selleckchem.com/pr....oducts/pf-06463922.h
Importantly, SIRT2's protective effects were not evident in lung cancer cells in vitro or in tumors in vivo. Taken together, our results identified SIRT2's function in the NER pathway as a key underlying mechanism of preventing CIPN, warranting future investigation of SIRT2 activation-mediated neuroprotection during platinum-based cancer treatment.Neutrophil accumulation is associated with lung pathology during active tuberculosis (AT. However, the molecular mechanism(s) by which neutrophils accumulate in the lung and contribute t
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