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In keeping with past studies, we look for a complete inhibitory effect of the edge, however with an obvious asymmetry, where the inhibitory effect is more powerful from Saxony to Czechia than vice versa. Moreover, we identify marked spatial variation along the border in the degree to which disease spread was inhibited. In specific, the region around Löbau in Saxony has been a hotspot for cross-border illness transmission. The capability to recognize infection flux hotspots along worldwide edges can help to modif