https://www.selleckchem.com/pr....oducts/GSK872-GSK239
Meta-regression models showed that increasing differences in E/A ratio (Z-score -2.002; P=.045), E/E' ratio (Z-score -2.181; P=.029) and left atrial diameter (Z-score -1.951; P=.05 were linked to higher differences in FMD values between cases and controls. Impaired endothelial function can be documented in HFpEF, with the possibility of a direct association between the severity of diastolic and endothelial dysfunction. Targeting endothelial dysfunction through pharmacological and rehabilitation strategies may represent an a