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In conclusion, these applications and physical properties of AFPs can be further explored to meet other industrial players. Designing the peptide-based AFP can also be done to subsequently improve its function.In this paper, a novel interference free dual-hop device-to-device (D2D) aided cooperative relaying strategy (CRS) based on spatial modulation (SM) (termed D2D-CRS-SM) is proposed. In D2D-CRS-SM, two cellular users (e.g., a near user (NU) and a relay-aided far user (FU)) and a pair of D2D transmitter (D1)-receivers (D2) are serve