https://www.selleckchem.com/products/ab928.html
BACKGROUND AND AIMS While triptans are used to treat migraine, there is evidence that they also reduce inflammation induced pain at the spinal level. The cellular mechanisms underlying this spinal enhancement are unknown. We examined whether inflammation alters sumatriptan modulation of synaptic transmission in the rat spinal dorsal horn. EXPERIMENTAL APPROACH 3 - 4 days following intraplantar injection of complete Freund's adjuvant (CFA), or saline, whole cell recordings of evoked glutamatergic excitatory postsynaptic currents (EPSCs) we
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