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The areas under the miR-320 family member ROC curves were 0.9037 (P less then 0.0001), 0.7515 (P = 0.0002), 0.9647 (P less then 0.0001), 0.8064 (P less then 0.0001) and 0.9019 (P less then 0.0001). Regarding Kaplan-Meier analysis, high miR-320c and miR-320d expression were related to shorter overall survival (OS). Moreover, multivariate analysis revealed the independent prognostic value of miR-320d for OS in MDS. The expression of miR-320 family members was up-regulated in MDS, and miR-320 family members could serve as candidat