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© 2020 The community for used Microbiology.BACKGROUND Niemann-Pick infection type C is an autosomal-recessive, lysosomal storage space disorder with variable age of beginning and a heterogeneous medical presentationthat includes neurologic, psychiatric, and visceralfindings.Serial intrathecal injections of 2-hydroxypropyl-beta-cyclodextrin are being examined as a treatment modality for Niemann-Pick illness type C with a subset of patients needing anesthesia with this treatment.