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010 and p=0.011, respectively). The mean bursting pressure levels were 174.29±44.68 mmHg in the control group, 223±38.6 mmHg in collagen group, and 223.33±42 mmHg in the gentamicin-impregnated collagen group, showing that the mean bursting pressure levels were significantly lower in the control group than the other groups (p=0.027 and p=0.029, respectively). CONCLUSIONS This study suggests that colo-colonic anastomosis coverage using materials incorporating collagen alone or gentamicin-impregnated collagen increases the safety of anasto