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Overexpression of HDAC5 mitigated the calcium deposition induced by miR-134-5p. Our results suggest that a Pi-induced increase of miR-134-5p may cause vascular calcification through repression of HDAC5.DRB1*0897 differs from DRB1*08030201 by one nucleotide substitution at position 485 in exon 3. Sepsis induces pulmonary P2X receptor (P2X R) expression and P2X R-knockout reduced lung inflammation in mice. The present study investigated the expression of circular RNA (circRNA) and mRNA in sepsis-induced acute lung injury (ALI) treated with