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To address such restrictions, we've created new technologies to organize thermostable, single-shot, prime-boost microparticle vaccines. Antigen/adjuvant formulations containing glass-forming polymers and trehalose initially tend to be spray-dried to create glassy microparticles that confer thermostability. Atomic layer deposition (ALD) reactions conducted in fluidized bedrooms tend to be then utilized to coat the microparticles with defined numbers of molecular layers of alumina that modula