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In conclusion, this meta-analysis suggested that high expression of nestin was significantly associated with OS of NSCLC. In conclusion, this meta-analysis suggested that high expression of nestin was significantly associated with OS of NSCLC. Lung adenocarcinoma has increased incidence over the past years and is the cause for almost 50% of deaths attributable to lung cancer. The objective of this paper is to identify activated pathways associated with lung adenocarcinoma based on gene co-expression network analysis. Kyoto Encyclopedia of Genes and