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Medical periodontal variables, such as for instance probing pocket level (PPD), clinical accessory degree (CAL), percent of plaque and bleeding on probing (BOP) were evaluated, and non-stimulated whole saliva ended up being gathered from all patients before periodontal therapy and after 1 year of follow-up. A bead-based multiplex assay assessed cytokines. When you look at the chronic periodontitis group, periodontal treatment significantly improved clinical paramet