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430, Df = 581, P less then 0.05, Sig. at 0.00, and preventive practices (F = 11.075, Df = 581, P less then 0.05, Sig. at 0.00 of residents of Southwest Nigeria, respectively. The study concludes that health communication channels such as the television, Internet, radio, newspaper, and health workers positively influence the behavioural practices of residents of Southwest Nigeria. The study recommends the development of a nationwide communication system on HBV targeted at putting an end to the disease in line with the 2030 global eli