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The pH-dependent development of the triplex construction then produced the pH-related nanoswitch/miRNA hybrid, and also the metastable nanoswitch created a clear sign enhance at pH 6.8. Amazingly, the pH condition at 6.8 for the greatest nanoswitch/miRNA hybrid is in line with the suitable DSN catalysis, which paves the way in which for a first-rank DSN sign amplification (DSNSA) technique for the single-base discerning ability associated with the h
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