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The aim of this study was to assess active tuberculosis-related deaths in Shenzhen city of China to identify major causes of mortality in different age groups. Medical records of mortality cases of patients with active TB diagnosed during 2013-2018 were reviewed. All TB deaths were classified into two broad age groups (the young group 18-65 years old and the elderly group 65 years old). Causes of death were analyzed based on medical records. A total of 279 mortality cases of active TB were reviewed during the study period. Among them,