https://www.selleckchem.com/pr....oducts/Ispinesib-mes
Contrast-induced acute kidney injury (CIAKI) is the third leading cause of acute renal failure in hospitalized patients. This study was aimed to investigate whether atorvastatin could upregulate the expression of hydrogen sulfide (H S) and hence protect against CIAKI. We treated male rats and NRK-52E cells by iopromide to establish and models of CIAKI. Pretreatment with atorvastatin was given in CIAKI rats to investigate its effect on CIAKI. We collected serum and urine samples to detect renal function. We obtained