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5 to 99.8), positive likelihood ratio (11.1, 95% CI 1.7 to 72.8), and low negative likelihood ratio (0.08, 95% CI 0.01 to 0.6) for detecting portal hypertension. Our study suggests that the biofluid mechanics-based model was able to accurately predict free portal pressure and detect portal hypertension in canines. With further research and validation, this model might be applicable for calculating human portal pressure, detecting portal hypertensive patients, and evaluating disease progression and treatment efficacy. Our study suggests
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