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Collagen kind XII alpha 1 chain (COL12A1) is involving real human disease progression. Nevertheless, the phrase structure as well as the function of COL12A1 inintrahepatic cholangiocarcinoma (iCCA) stay unknown. The current study had been done to evaluate the role of COL12A1 in iCCA.Promoter hypermethylation-induced miR-424-5p downregulation contributes to COL12A1 upregulation in iCCA. COL12A1 is a promising druggable target for epigenetic treatment of iCCA.The YTH N6-methyladenosine RNA binding proteins (YTHDF
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