https://www.selleckchem.com/pr....oducts/ono-ae3-208.h
Finally, we found the impact of negative selection for coding CpG mutations resulting in amino acid change. CONCLUSIONS This study provides the first unbiased rate of CG TA substitution at the CpG dinucleotide contexts, using population-scale human genome sequencing data. Our findings provide insights into the dynamics of the mutation acquisition in the human genome.BACKGROUND Polydactyly is one of the most common congenital limb dysplasia in many animal species. Although preaxial polydactyly (PPD) has been comprehensively stud