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The carbon dots (C-dots) mediated Sn2Ta2O7/SnO2 heterostructures with spongy structure were successfully assembled by simple hydrothermal route. The photocatalytic removal efficiency of amoxicillin (AMX, 20 mg L-1) over C-dots/Sn2Ta2O7/SnO2 was estimated to reach up 88.3% within 120 min simulated solar light irradiating. Meanwhile, the HPLC-MS/MS analysis and density functional theory (DFT) computation were examined to clarify the photo-degradation pathway of AMX. The mechanism investigation proposed that with the modification of C-dot