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Also therefore, tau protein pathology is amply present in these diseases. Both α-Syn and tau can exist as polymorphic aggregates, a phenomenon which has been commonly examined, mostly in their fibrillar assemblies. We now have previously discovered that in addition to α-Syn oligomers, oligomeric tau can also be contained in mental performance areas of clients with PD and alzhiemer's disease with Lewy bodies (DL. But, the effect of connection between polymorphic α-Syn oligomers and tau is not