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Finding the Best Medication For ADHD The most frequently prescribed medication for ADHD is stimulants. They include methylphenidates and amphetamines. Short-acting stimulants start working in less than one hour and need to be taken several times a day. Long-acting stimulants can last for up to 16 hours and are typically taken only once a day. Your doctor may prescribe antidepressants, or other medications "off-label" to treat ADHD symptoms. These drugs are approved to treat disorders like depression or anxiety. Stimulants The most common medication
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