https://www.selleckchem.com/pr....oducts/ar-c155858.ht
At a somatic level, the most common driver mutation is BRAF, second most common NRAS, third NF1 and increasing numbers of additional rarer mutations are being identified such as in TP53. It is of note that the BRAF and NRAS mutations are not CT accepted as characteristic of ultraviolet light induced mutations.Cutaneous malignant melanoma is a rare and aggressive cancer of the melanocytes of the skin. The majority of cutaneous melanomas are cured surgically, but a significant proportion are either metastatic at presentation or rec
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