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A 57-year-old feminine patient diagnosed with Fabry condition 11 years previously, served with hyperhidrosis, hypoacusis, and angiokeratoma on the fingers. Her previous pathological history included an episode of ischemic stroke prior to the age 40 years and chronic severe thrombosis in the right lower limb, 1 year previously, which was indeed addressed with stent angioplasty, with short-term improvement accompanied by current relapse of the condition. Thrombotic activities fit the standar